This is a run that will get you 5769 blood echoes every three minutes thats 115,380 an hour the best weapons to use are the rifle spear and the ludwig holy blade but its really just preference.
I think with a game like this that strives to challenge you, make you think every move you make, you shouldnt do this on your 1st playthrough maybe once you've finished it you can do it so that way the gameplay isnt completely ruined