1. Basic Information
Let's get started on the basics. The Tactical Nuke (or Nuke for short) is a unlock-able killstreak in MW2. It requires 25 kills (or 24 kills with Hardline). To sum it up, it kills everyone (including your team) on the map plus any air support (UAVs, Pave Low, etc.) in the air. It is an automatic win for your team, no matter if you are losing. The next chapter is the classes required to get the Nuke.

2. Classes
This section is about classes for you to get your nuke. These are my classes, so they might not suit your needs, but I get the nuke with them so they work for me. The main gun I use is the M4A1 with Red Dot Sight, Silencer, or FMJ. I use the silencer because when you shoot, you do not appear on the enemies' radar. Custom Class 1
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So it is the M4A1 (Silencer, Red Dot Sight, or FMJ) with the Striker Grip, FMJ, or Red Dot Sight) with Bling Pro, Hardline Pro, and Commando OR Steady Aim

That's basically all there is. You always want a long to medium range gun.

Here are my Killstreaks:
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AFGHAN
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You will want to hide in the bunker (or by Flag B in Domination) and pick people off.

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You will want to hide in the building by Flag B in Domination. It is a good spot to camp and kill people when they go to B.

Estate

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You want to hide in the manor by Flag A in Domination. You get an overview of the map, but be careful because people can snipe you.

Favela

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You will want to hide in the house in between Flags A and B. It is a good lookout of both flags.

Highrise

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I hide on the ledge looking at C because people don't expect you being there and they can't see you.

Invasion

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I usually hide by Flag B because many people try to take the flag and don't see you camping.

Karachi

I hide on the roof overlooking B.

Quarry

I hide by in the warehouse by A because many people try to go that way and you pick them off.

Rundown

This is my favorite map by far. I hide by the bridge on the right if you are the Militia.
I will add more maps later.